Senior Laboratory Technologist - Clinical Genomics

Responsibilities

• Perform nucleic acid extraction.

• Perform manual and automated extraction and purification of DNA/RNA from various clinical specimens, including blood, tissue, and bone marrow.

• Ability to independently prepare DNA libraries for high-throughput sequencing and utilize sequencing platforms for basic genomic analysis.

• Operate and troubleshoot Next Generation Sequencing equipment.

• Perform PCR (including RT-PCR and fluorescent PCR).

• Perform QA/QC procedures and documentation.

• Perform troubleshooting to solve problems as they arise.

• Assist with training of laboratory medical technicians in new methods to implement clinical testing and workflows.

• Assist in maintaining CAP/ISO Standards and working with the quality department to keep the laboratory in compliance with regulations as they relate to test validation.

• Reading of pertinent literature related to the specialty to maintain current knowledge in this dynamic, rapidly evolving, field.

• Ensure validity of laboratory data reported.

• Participate in validation activities and participate in daily operation of the lab platforms.

• Participate in experimental design and instrument set-up.

• Public Contribute to maintaining a Quality environment and participate actively in SOP writing and revision.

• Develop next-generation sequencing sample prep methods, both by utilizing standard molecular biology processes and creating novel solutions.

• Coordinate and support all stages of the transition of new products from development to product release, such as validating processes, establishing quality controls.

• Perform duties assigned by Line manager.

• Aware of GCLP and GCP that apply to their work and be fully aware of the function they are to perform.

• Responsible for recording raw data promptly, accurately and in compliance with GCLP and are responsible for the quality of their data.

• Responsible for following the instructions given in the clinical protocol, analytical plans, and SOPs.

Qualifications

• Bachelor’s degree or above in Medical Laboratory or other related majors is preferred.

• Experience in automated workstation system.

• Fluent in English oral and written.

• Good communication skills.

• Molecular Biology with genomics background.

• Experience in Next Generation Sequencing (NGS) and/or Microarray techniques preferred.

• Minimum 2 years of experience in genomics.

• Experience in CAP or ISO15189 certified laboratory is preferred.

• DOH License.